This is an advanced course in the use of modern
instrumentation, both spectroscopic and chromatographic techniques, for the
solution of chemical problems. This
course discusses relationships between functionality and the observed
spectroscopic properties of organic molecules.
These relationships are then rationalized and used to logically deduce
structures of unknown compounds.
Chromatographic techniques and principles will be emphasized. Subsequently, five different spectroscopic
methods, Nuclear Magnetic Resonance, Mass Spectrometry, Infrared, Ultraviolet
Spectroscopy, and Chiroptical Spectroscopy will be applied in the structural
assignment of unknown compounds. The
principles behind these methods will be discussed. There will be considerable emphasis on
problem solving to determine molecular structure utilizing all available spectroscopic data. Some lecture classes will be practical
demonstration of the concepts presented.